WL, MW, HZ and LZ designed the research study. WL and MW conceived and supervised the study. HZ, LZ and SW performed experiments and data collection. DY, JM, SW and XH analyzed the data. WZ and MT performed visualization. HZ wrote the manuscript. All authors contributed to manuscript revisions, read, and approved the final manuscript, and agree to be accountable for all aspects of the work. All authors agree to the submission and publication of the manuscript.
Not applicable.
We thank the TCGA Research Network, the Gene Ontology Consortium, and the Human Protein Atlas for making their data and resources publicly available. We are grateful to the reviewers for their constructive feedback. We also thank Ejear for professional English-language editing; the company had no role in study design, data collection, analysis, interpretation, or the decision to publish.
This work was supported by the Scientific Research Initiation Funding Project of the Affiliated Huai’an No.1 People’s Hospital of Nanjing Medical University (TCT201802).
The authors declare no conflict of interest.
Artificial intelligence (AI) and AI-assisted technologies were used in the preparation of this manuscript for purposes such as language editing, grammar checking, and improving clarity of expression. All content was reviewed and verified by the authors to ensure accuracy and compliance with academic standards. No generative AI tools were used for data analysis, scientific interpretation, or creation of original results.