Abbreviations

DSG, degraded sulfated galactan; DSGO, degraded sulfated galactan supplemented with octanoyl ester; ECM, extracellular matrix; FTIR, Fourier-transform infrared spectroscopy; GPC, gel permeation chromatography; MT, Masson’s trichrome; NLAC, National Laboratory Animal Center; NMR, nuclear magnetic resonance; SG, sulfated galactan; SP, sulfated polysaccharide; WHO, World Health Organization.

Availability of Data and Materials

All data generated and analyzed during this study are available from the corresponding author on reasonable request.

Author Contributions

KJ, AP, KW, JK and TR conducted and designed the experiment. KJ, AP, WS and TR performed the experiments and verified data quality. KJ, AP, WS, KW, JK and TR validated the data. KJ, AP, WS and TR wrote the original manuscript. KW, JK and TR reviewed and edited the manuscript. All authors have read and agreed to the published version of the manuscript. All authors contributed to editorial changes in the manuscript. All authors have participated sufficiently in the work to take public responsibility for appropriate portions of the content and agreed to be accountable for all aspects of the work in ensuring that questions related to its accuracy or integrity.

Ethics Approval and Consent to Participate

The study received approval from the Animal Ethics Committee at the University of Phayao Faculty of Medical Science, in line with the Ethics of Animal Experimentation by the National Research Council (Ethical Approval Number: 64 01 04 011).

Acknowledgment

We would like to acknowledge Dr. Dylan Southard for editing the manuscript via the KKU Publication Clinic (Thailand).

Funding

This research was supported by the University of Phayao and the Thailand Science Research and Innovation Fund (Fundamental Fund 2021; Grant No. FF64-RIM033), along with the National Research Council of Thailand (NRCT; Grant No. N42A650206).

Conflict of Interest

The authors declare no conflict of interest.

Supplementary Material

Supplementary material associated with this article can be found, in the online version, at https://doi.org/10.31083/j.fbl2911388.